产品货号:
Z12472
中文名称:
Calpain-6/CAPN6抗体
英文名称:
Anti-Calpain-6/CAPN6 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Calpain-6/CAPN6 Antibody |
指标别名 | calpain 6,Calpain like protease X linked,Calpamodulin,CalpM,CANPX,CAPN6,CAPNX |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | CAPN6 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | CAPN6 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human CAPN6.The immunogen is located within the last 50 amino acids of CAPN6. |
计算分子量 | 75kDa |
成分 | CAPN6 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | CAPN6 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Calpains make up a ubiquitously expressed,well-conserved family of calcium-dependent cysteine proteases.The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits.This large subunit possesses a cysteine protease domain,and both subunits possess calcium-binding domains.Calpains have been implicated in neurodegenerative processes as their activation can be triggered by calcium influx and oxidative stress.Calpain 6 (CAPN6) is most similar to Calpain 5;the C-terminal region of CAPN6 lacks homology to the calmodulin-like domain of other vertebrate calpains.CAPN6 is thought to be involved in the regulation of microtubule dynamics and cytoskeletal organization.CAPN6 has also been recently identified as an HIV dependency factor (HDF),suggesting that CAPN6 may be an important drug target in HIV treatment. |
Uniprot ID | Q9Y6Q1 |
基因名全称 | Calpain 6 |
蛋白名全称 | Calpain 6 |
推荐稀释比 | CAPN6 antibody can be used for the detection of StrepII by Western blot at 0.5 ~ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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